Cancer Pain: Understanding and Managing This Neuropathic Condition

For many patients battling cancer, the disease itself is only part of the challenge. Cancer pain, a type of neuropathic or nerve-related pain, can be an extremely difficult side effect that significantly impacts quality of life. At the Chicago Institute for Neuropathic Pain, our team specializes in understanding and effectively treating cancer pain to help patients find relief.

What is Cancer Pain?


Cancer pain refers to any pain that results from cancer itself or the treatments used to manage the disease. It falls under the category of neuropathic pain, which occurs when there is damage, dysfunction or irritation to the nerves that transmit pain signals to the brain.

Cancer pain can arise for various reasons, including:

  • Tumor growth pressing on organs, bones or nerves

  • Cancer treatments like chemotherapy or radiation damaging nerves

  • Post-surgical pain after cancer-related procedures

  • Persistent pain in the area where cancer was initially located

This type of neuropathic pain tends to be chronic, moderate to severe, and resistant to typical pain medications. Proper assessment and specialized neuropathic pain management are crucial.

Unique Cancer Pain Challenges

What makes cancer pain so difficult to treat? Beyond the obvious emotional toll, there are physiological reasons this neuropathic condition is particularly complex:

  • Pain pathways are altered by cancer itself and harsh treatments

  • Ongoing tissue/nerve injury causes hypersensitivity and overactive signaling

  • Opioid tolerance may develop, reducing medication effectiveness

  • Side effects of cancer therapies can worsen existing pain

Additionally, unrelenting cancer pain takes a mental, physical and emotional toll that can complicate treatment approaches. Effective pain management must address the whole patient experience.

Tailored Neuropathic Pain Treatment Plans

At our clinic, we believe no two cases of cancer pain are alike. Every patient deserves a personalized assessment and care plan tailored for their specific condition, cancer type/stage, concurrent treatments and personal needs.

Our multimodal approach to treating neuropathic cancer pain may incorporate:

  • Medications: Antidepressants, anticonvulsants, anesthetics and opioids

  • Interventional procedures: Nerve blocks, spinal cord stimulation

  • Complementary therapies: Acupuncture, massage, mindfulness

  • Psychological support: Coping strategies, behavioral techniques

The goal is to disrupt and desensitize abnormal pain signaling through different mechanisms while also providing coping tools for chronic pain management.

Restoring Function and Quality of Life

Uncontrolled neuropathic cancer pain can be debilitating, impacting every aspect of a patient's life from sleep and appetite to mood and mobility. Our interdisciplinary team works to get this complex condition under control so patients can prioritize healing while restoring function and quality of life.

Whether you are currently undergoing cancer treatment or have persistent pain following therapy, effective neuropathic pain relief is possible. Don't let cancer pain continue to diminish your wellbeing - the Chicago Institute for Neuropathic Pain has the expertise to help you find your way back to a more comfortable, fulfilling life.

Schedule a consultation today to have your unique cancer pain situation evaluated. Regaining control over your neuropathic pain is within reach.